A useful definition has to survive awkward examples. Decide whether each system counts as a biocomputer in the broad sense used on this site.

A biocomputer uses biological material to perform a meaningful information-processing role. A device can be neural-inspired without containing living tissue, and biological tissue can be present without being used as a computer.

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The boundary matters

Biocomputing is broader than living-neuron computing. DNA logic and engineered-cell circuits can qualify too. Neuromorphic chips and ordinary artificial neural networks use electronic substrates, while a brain–computer interface describes the connection between a nervous system and a machine.

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