CL1
Cortical Labs
- Substrate
- 2D neuronal culture
- Interface
- Custom silicon MEA
- Use
- Programmable closed-loop experiments
- Evidence
- Commercial platform
Source checked 2026-08-17
Biocomputer database
11 living-neural systems and platforms, labelled by substrate, access and the strongest public evidence behind each entry.
11 systems
| System | Organisation | Biological substrate | Interface | Demonstrated use | Evidence |
|---|---|---|---|---|---|
| CL1Checked 2026-08-17 | Cortical Labs | 2D neuronal culture | Custom silicon MEA | Programmable closed-loop experiments | Commercial platform |
| Goal-directed cart-pole organoidsChecked 2026-08-17 | UC Santa Cruz and collaborators | 3D cortical organoids | Electrophysiology + closed loop | Goal-directed pole balancing | Peer reviewed |
| Temporal-pattern BNNChecked 2026-08-17 | Tohoku University and collaborators | 2D modular cortical culture | Microfluidics + high-density MEA | Autonomous temporal-pattern generation | Peer reviewed |
| BrainowareChecked 2026-08-17 | Indiana University and collaborators | 3D brain organoid | High-density MEA | Reservoir computing | Peer reviewed |
| FinalSpark NeuroplatformChecked 2026-08-17 | FinalSpark | 3D neural organoids | MEA + microfluidics + remote API | Remote wetware experiments | Peer-reviewed platform |
| DishBrainChecked 2026-08-17 | Cortical Labs and collaborators | 2D cortical neurons | High-density MEA | Closed-loop Pong | Peer reviewed |
| Braille organoid classifierChecked 2026-08-17 | University of Bristol and collaborators | 3D forebrain organoids | Low-density MEA | Tactile Braille classification | Preprint |
| 3D-MINDChecked 2026-08-17 | Princeton University | 3D cultured neural network | 3D flexible electrode array | Reservoir computing + chronic stimulation | Peer reviewed |
| Mind in Vitro platformChecked 2026-08-17 | University of Illinois Urbana-Champaign consortium | 2D cultured neural networks | Open modular electrophysiology platform | Programmable living-neuron research | Peer reviewed |
| TBC Neural OptimizerChecked 2026-08-17 | The Biological Computing Co. | Living neural networks → software | MEA experiments + software adapter | Video-model optimization | Company demonstration |
| Neurorium BNN demonstrationsChecked 2026-08-17 | Neurorium | Biological neural networks | Electrophysiology + software | Visual memory, classification and control demos | Company demonstration |
Goal-directed cart-pole organoids
UC Santa Cruz and collaborators
- Substrate
- 3D cortical organoids
- Interface
- Electrophysiology + closed loop
- Use
- Goal-directed pole balancing
- Evidence
- Peer reviewed
Source checked 2026-08-17
Temporal-pattern BNN
Tohoku University and collaborators
- Substrate
- 2D modular cortical culture
- Interface
- Microfluidics + high-density MEA
- Use
- Autonomous temporal-pattern generation
- Evidence
- Peer reviewed
Source checked 2026-08-17
Brainoware
Indiana University and collaborators
- Substrate
- 3D brain organoid
- Interface
- High-density MEA
- Use
- Reservoir computing
- Evidence
- Peer reviewed
Source checked 2026-08-17
FinalSpark Neuroplatform
FinalSpark
- Substrate
- 3D neural organoids
- Interface
- MEA + microfluidics + remote API
- Use
- Remote wetware experiments
- Evidence
- Peer-reviewed platform
Source checked 2026-08-17
DishBrain
Cortical Labs and collaborators
- Substrate
- 2D cortical neurons
- Interface
- High-density MEA
- Use
- Closed-loop Pong
- Evidence
- Peer reviewed
Source checked 2026-08-17
Braille organoid classifier
University of Bristol and collaborators
- Substrate
- 3D forebrain organoids
- Interface
- Low-density MEA
- Use
- Tactile Braille classification
- Evidence
- Preprint
Source checked 2026-08-17
3D-MIND
Princeton University
- Substrate
- 3D cultured neural network
- Interface
- 3D flexible electrode array
- Use
- Reservoir computing + chronic stimulation
- Evidence
- Peer reviewed
Source checked 2026-08-17
Mind in Vitro platform
University of Illinois Urbana-Champaign consortium
- Substrate
- 2D cultured neural networks
- Interface
- Open modular electrophysiology platform
- Use
- Programmable living-neuron research
- Evidence
- Peer reviewed
Source checked 2026-08-17
TBC Neural Optimizer
The Biological Computing Co.
- Substrate
- Living neural networks → software
- Interface
- MEA experiments + software adapter
- Use
- Video-model optimization
- Evidence
- Company demonstration
Source checked 2026-08-17
Neurorium BNN demonstrations
Neurorium
- Substrate
- Biological neural networks
- Interface
- Electrophysiology + software
- Use
- Visual memory, classification and control demos
- Evidence
- Company demonstration
Source checked 2026-08-17
Evidence labels
Peer reviewed Published research. Replication and benchmark quality remain separate questions.
Preprint Public manuscript awaiting peer review.
Company demonstration Product or demonstration whose performance claims come primarily from the developer.